| Lexington Sporting Club vs. Hartford Athletic FC | 3-8-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Indy Eleven | 3-22-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. San Antonio FC | 3-29-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Las Vegas Lights FC | 4-12-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Monterey Bay FC | 4-19-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Loudoun United FC | 4-26-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Louisville City FC vs. Lexington Sporting Club | 5-1-2025
Thursday
TBD | Lynn Family Stadium in Louisville, KY | View Tickets |
| Loudoun United FC vs. Lexington Sporting Club | 5-10-2025
Saturday
TBD | Segra Field in Leesburg, VA | View Tickets |
| Lexington Sporting Club vs. FC Tulsa | 5-18-2025
Sunday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Tampa Bay Rowdies | 5-24-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Monterey Bay FC vs. Lexington Sporting Club | 6-7-2025
Saturday
TBD | Cardinale Stadium in Marina, CA | View Tickets |
| Lexington Sporting Club vs. New Mexico United | 6-14-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Colorado Springs Switchbacks FC | 6-21-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Phoenix Rising FC vs. Lexington Sporting Club | 7-4-2025
Friday
TBD | Phoenix Rising FC Stadium in Phoenix, AZ | View Tickets |
| Miami FC vs. Lexington Sporting Club | 7-12-2025
Saturday
TBD | Pitbull Stadium in Miami, FL | View Tickets |
| Sacramento Republic FC vs. Lexington Sporting Club | 7-19-2025
Saturday
TBD | Heart Health Park in Sacramento, CA | View Tickets |
| Lexington Sporting Club vs. Louisville City FC | 7-26-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Phoenix Rising FC | 8-9-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| San Antonio FC vs. Lexington Sporting Club | 8-16-2025
Saturday
TBD | Toyota Field - TX in San Antonio, TX | View Tickets |
| Lexington Sporting Club vs. Oakland Roots SC | 8-23-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Las Vegas Lights FC vs. Lexington Sporting Club | 8-30-2025
Saturday
TBD | Cashman Field in Las Vegas, NV | View Tickets |
| Lexington Sporting Club vs. North Carolina FC | 9-5-2025
Friday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| FC Tulsa vs. Lexington Sporting Club | 9-6-2025
Saturday
TBD | ONEOK Field in Tulsa, OK | View Tickets |
| Lexington Sporting Club vs. Orange County SC | 9-12-2025
Friday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Detroit City FC vs. Lexington Sporting Club | 9-20-2025
Saturday
TBD | Keyworth Stadium in Hamtramck, MI | View Tickets |
| New Mexico United vs. Lexington Sporting Club | 9-28-2025
Sunday
TBD | Rio Grande Credit Union Field at Isotopes Park in Albuquerque, NM | View Tickets |
| Lexington Sporting Club vs. El Paso Locomotive FC | 10-11-2025
Saturday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Lexington Sporting Club vs. Sacramento Republic FC | 10-17-2025
Friday
TBD | Lexington SC Stadium in Lexington, KY | View Tickets |
| Oakland Roots SC vs. Lexington Sporting Club | 10-25-2025
Saturday
TBD | Oakland Coliseum in Oakland, CA | View Tickets |
